STUDIES ON THE ANTI-INFLAMMATORY EFFECT OF THE AQUEOUS EXTRACT OF THE LEAVES OF VITEX TRIFOLIA L. IN ALBINO RATS.

Authors

  • A. PFUZIA Post graduate traineeImphal,Manipur, India
  • R.K. BHARATI DEVI Professor Department of Pharmacology, Regional Institute of Medical Sciences,Imphal,Manipur, India
  • KH. SHARATCHANDRA Professor Department of Pharmacology, Regional Institute of Medical Sciences,Imphal,Manipur, India
  • B. N. DEBASHREE Post graduate traineeImphal,Manipur, India
  • BANYLLA SN Post graduate traineeImphal,Manipur, India
  • KH. SANIA MONICA Post graduate traineeImphal,Manipur, India

Keywords:

Anti-inflammatory, carrageenan, granuloma pouch, formaldehyde arthritis

Abstract

Vitex trifolia belongs to the family lamiaceae. The anti-inflammatory property of the aqueous extract of the leaves of Vitex trifolia L. was studied by carrageenan induced paw oedema, granuloma pouch and formaldehyde induced arthritis method. in albino rats. The extract was administered at the varying doses of 500, 1000 & 2000 mg/kg body weight per orally to three groups of six animals each. Increasing the doses of the test drug produced signicant (p<0.001) increased in percentage of inhibition of paw oedema and significant inhibition of exudate formation. The extract shows significant anti-inflammatory activity when compared with the control and comparable efficacy with the standard. The present study suggests that the aqueous extract of the leaves of vitex trifolia L. has anti-inflammatory property.

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Published

30.06.2013

How to Cite

A. PFUZIA, R.K. BHARATI DEVI, KH. SHARATCHANDRA, B. N. DEBASHREE, BANYLLA SN, & KH. SANIA MONICA. (2013). STUDIES ON THE ANTI-INFLAMMATORY EFFECT OF THE AQUEOUS EXTRACT OF THE LEAVES OF VITEX TRIFOLIA L. IN ALBINO RATS. International Journal of Pharma and Bio Sciences, 4(2), 588–593. Retrieved from https://ijpbs.net/index.php/journal/article/view/2206

Issue

Volume 4, Issue 2, 2013

Section

Research Articles

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