EVALUATION OF IN-VITRO IMMUNOMODULATORY ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACT OF CAPPARIS MOONII

Authors

  • VANITA G.KANASE Associate Professor, Gahlot Institute of Pharmacy, Koparkhairane, Navi Mumbai, Maharashtra, IndiaNIMS University Jaipur, Rajasthan, India;
  • DR.BRIJENDRA B.JAIN Associate Director, YSPM’s - Yashoda Technical Campus, Satara, Maharashtra, IndiaNIMS University Jaipur, Rajasthan, India;
  • DR.PRAMILA YADAV Professor, Department of Pharmacology, Dr. D.Y. Patil Medical College, Navi Mumbai, Maharashtra, IndiaNIMS University Jaipur, Rajasthan, India

Keywords:

Capparis moonii, peritoneal murine macrophages, nitric oxide, superoxides, phagocytic index

Abstract

The present study was intended to evaluate the in-vitro immunomodulatory activity of aqueous and ethanolic extract of dried fruits of Capparis moonii Wight. Effect of both the extracts were evaluated at various concentrations (832 μg/ml to 6.5 μg/ml) for secretion of variouesmediators like nitric oxide, superoxide, lysosomal enzyme etc of isolated murine peritoneal macrophages. Both the extracts showed in-vitro phagocytic stimulation of, lysosomal enzyme and myeloperoxidase activity and nitric oxide in peritoneal mouse macrophages. In-vitro phagocytic index showed significant results and thus proving the need for confirmation through in-vivo studies.

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Published

30.06.2013

How to Cite

VANITA G.KANASE, DR.BRIJENDRA B.JAIN, & DR.PRAMILA YADAV. (2013). EVALUATION OF IN-VITRO IMMUNOMODULATORY ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACT OF CAPPARIS MOONII. International Journal of Pharma and Bio Sciences, 4(2), 344–352. Retrieved from https://ijpbs.net/index.php/journal/article/view/2177

Issue

Volume 4, Issue 2, 2013

Section

Research Articles

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