CHEMICAL INFORMATION FROM GC-MS STUDIES OF METHANOLIC LEAF EXTRACT OF ANDROGRAPHIS PANICULATA AND DATURA METEL AND THEIR ANTIBACTERIAL ACTIVITY AGAINST ISOLATED PSEUDOMONAS AERUGINOSA (PB112) STRAIN

Authors

  • SOMERITA PANDA Parasitology Laboratory, Department of Zoology, University of Kalyani, Kalyani, West Bengal, India
  • P.K.BANDYOPADHYAY Parasitology Laboratory, Department of Zoology, University of Kalyani, Kalyani, West Bengal, India

Keywords:

Andrographis paniculata, Datura metel, P.aeruginosa, antibacterial activity, GC-MS analysis.

Abstract

The present study was carried out to determine the phytochemical profile and antibacterial activity of Andrographis paniculata and Datura metel extracts. For the present investigation, extracts of A. paniculata and D.metel were prepared by extraction in methanol, chloroform, acetone and benzene and were compared for their antibacterial activity. The antibacterial activities were assessed by measuring the diameter of the inhibition zones by Disc diffusion method. In comparison to this different extracts, the methanol extract showed better antibacterial activity against the isolated P.aeruginosa bacterial strain tested. The chemical composition of methanol extracts of these two plants were investigated by GC-MS, while the mass spectra of the compounds found in the extract was matched with the NIST and WILEY library.

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Published

31.03.2013

How to Cite

SOMERITA PANDA, & P.K.BANDYOPADHYAY. (2013). CHEMICAL INFORMATION FROM GC-MS STUDIES OF METHANOLIC LEAF EXTRACT OF ANDROGRAPHIS PANICULATA AND DATURA METEL AND THEIR ANTIBACTERIAL ACTIVITY AGAINST ISOLATED PSEUDOMONAS AERUGINOSA (PB112) STRAIN. International Journal of Pharma and Bio Sciences, 4(1), 909–915. Retrieved from https://ijpbs.net/index.php/journal/article/view/1977

Issue

Volume 4, Issue 1, 2013

Section

Research Articles

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