KINETIC MODELING AND DISSOLUTION PROFILES COMPARISON: AN OVERVIEW

Authors

  • HUSSAIN LOKHANDWALA School of Pharmacy and Technology Management, SVKM’S NMIMS, shirpur (Dhule), Maharashtra, India - 425405.
  • ASHWINI DESHPANDE School of Pharmacy and Technology Management, SVKM’S NMIMS, shirpur (Dhule), Maharashtra, India - 425405.
  • SHIRISH DESHPANDE. School of Pharmacy and Technology Management, SVKM’S NMIMS, shirpur (Dhule), Maharashtra, India - 425405.

Keywords:

Dissolution, drug release kinetic models, model dependent method, model independent method, statistical model, pairwise comparison.

Abstract

This review shares different mathematical models used to determine the kinetics of drug release from delivery systems. It consists of an overview of applied method for comparison like model dependent, model independent and statistical model. The mathematical modeling can finally help to optimize the design of a therapeutic device to yield a system with programmed release rate characteristics which is now a  prerequisite for controlled release drug delivery system. For the ease of application of these models linear forms to plot the graphs were also discussed. This review also consists of various software programs  available to describe the release kinetics from therapeutic device.

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Published

31.03.2013

How to Cite

HUSSAIN LOKHANDWALA, ASHWINI DESHPANDE, & SHIRISH DESHPANDE. (2013). KINETIC MODELING AND DISSOLUTION PROFILES COMPARISON: AN OVERVIEW. International Journal of Pharma and Bio Sciences, 4(1), 728–737. Retrieved from https://ijpbs.net/index.php/journal/article/view/1958

Issue

Volume 4, Issue 1, 2013

Section

Review Articles

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