TO STUDY THE HAEMOGLOBINOPATHIES AND RATIO OF COPPER AND ZINC IN SINDHI COMMUNITY OF BHOPAL

Authors

  • M. KAUR Department of Biotechnology, RKDF University, Bhopal.
  • C.B.S.DANGI Department of Biotechnology, RKDF University, Bhopal.
  • H. SINGH People’s Medical College and Research Centre , Bhopal.

Keywords:

Beta–Thalassaemia, Sickle Cell Anaemia, NESTROFT, Sickling, Solubility, Copper /Zinc Ratio

Abstract

The genetic haemtological disorder such as beta–thalassaemia and sickle cell anaemia is one of the burning problems in India. The community wise study is of great help as it provides versatile information. A random cross-sectional study was conducted in 500 volunteers of Sindhi community belonging to all age groups and both sexes. The mass screening was done by help of NESTROFT, Sickling, Solubility and complete blood picture were performed on all samples along with BMI .Those positive for either one or both, screening tests were further analyzed for HbA2 by HPLC D-10.  120 positive cases of haemoglobinopathies   were further analyzed for copper /zinc ratio. 120 positive cases of haemoglobinopathies were having low level of zinc and high level of copper, the ratio of copper / zinc was high along with low BMI. The positive cases were having different clinical manifestations   along with liver and heart diseases in some cases.

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Published

31.03.2013

How to Cite

M. KAUR, C.B.S.DANGI, & H. SINGH. (2013). TO STUDY THE HAEMOGLOBINOPATHIES AND RATIO OF COPPER AND ZINC IN SINDHI COMMUNITY OF BHOPAL. International Journal of Pharma and Bio Sciences, 4(1), 672–691. Retrieved from https://ijpbs.net/index.php/journal/article/view/1952

Issue

Volume 4, Issue 1, 2013

Section

Research Articles

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