QSAR STUDIES OF SOME PYRAZOLONES AS ANTIMICROBIAL AGENT

Authors

  • KISHOR ARORA Department of Chemistry, Government Autonomous Postgraduate College, Datia-475 661, India
  • VEENA NATHANI Department of Chemistry, Government Kamla Raja (Autonomous) Postgraduate College, Gwalior-474009, India

Keywords:

Antimicrobial activity, Macrophomina phaseolina, Pyrazolones, QSAR

Abstract

In the present study Quantitative Structure Activity Relationship (QSAR) studies were performed on selected pyrazolone compounds as antimicrobial agent. The compoundshas been established on the basis of analytical methods and advanced spectroscopic techniques. Three compounds viz. 4-Amino antipyrine thiosemicarbazone (C-8), 1-(2-Chloro-5-sulfophenyl)-3-methyl-5-pyrazolone (C-9) and 1-(4-Sulfoamido phenyl)-3-methyl-5-pyrazolone (C-10) recorded significant antifungal activity against Macrophomina phaseolina.

Downloads

Published

31.03.2013

How to Cite

KISHOR ARORA, & VEENA NATHANI. (2013). QSAR STUDIES OF SOME PYRAZOLONES AS ANTIMICROBIAL AGENT. International Journal of Pharma and Bio Sciences, 4(1), 657–671. Retrieved from https://ijpbs.net/index.php/journal/article/view/1951

Issue

Volume 4, Issue 1, 2013

Section

Research Articles

Categories