ANTIDIABETIC ACTIVITY OF KARCHURE CHOORANAM ON ALLOXAN INDUCED DIABETIC RATS

Authors

  • K. NANDHAGOPAL Department of Pharmacology, Govt. Siddha Medical College, Arumbakkam, Chennai-600106, India
  • M.KANNIYAKUMARI Department of Pathology, Sri Santhigiri Siddha Medical College, Trivandrum, Kerala-695589,, India
  • J. ANBU Department of Pharmacology, School of Pharmaceutical Sciences, (VISTAS) Vels University, Pallavaram, Chennai-600117 India
  • V.VELPANDIAN Department of Pharmacology, Govt. Siddha Medical College, Arumbakkam, Chennai-600106, India

Keywords:

Phoenix dactylifera linn, Siddha system, Glibenclamide, Anti-diabetic activity, Alloxan

Abstract

Phoenix dactylifera linn (Arecaceae) commonly known as Date palm has been widely used in Siddha system of medicine for diabetes. The powder form of dried dates (Karchure chooranam) showed a significant inhibitory effect was screened at 500mg/kg, for the in vivo anti-diabetic activity on alloxan induced diabetic rats. Glibenclamide (10mg/kg) used as reference standard. Single dose (500 mg/kg) treatment with the siddha drug Karchure chooranam produced 69.34% anti-hyperglycaemic effect (antidiabetic effect). The trial drug showed a significant anti-diabetic activity (P<0.01) and were comparable with that of standard thus validating the traditional claim of the plant.

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Published

31.03.2013

How to Cite

K. NANDHAGOPAL, M.KANNIYAKUMARI, J. ANBU, & V.VELPANDIAN. (2013). ANTIDIABETIC ACTIVITY OF KARCHURE CHOORANAM ON ALLOXAN INDUCED DIABETIC RATS. International Journal of Pharma and Bio Sciences, 4(1), 434–439. Retrieved from https://ijpbs.net/index.php/journal/article/view/1930

Issue

Volume 4, Issue 1, 2013

Section

Research Articles

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