IN VITRO DETERMINATION OF ANTI-OXIDANT AND ANTI-BACTERIAL ACTIVITIES OF VITEX NEGUNDO LINN.

Authors

  • MURALI KRISHNA. T Department of Biotechnology, Chaitanya Post Graduate College, Kishanpura, Hanamkonda, Andhra Pradesh, India.
  • MEENA. G Department of Biotechnology, Chaitanya Post Graduate College, Kishanpura, Hanamkonda, Andhra Pradesh, India.
  • KAVYA. T Department of Biotechnology, Chaitanya Post Graduate College, Kishanpura, Hanamkonda, Andhra Pradesh, India.
  • SOMESHWAR. C Department of Biotechnology, Chaitanya Post Graduate College, Kishanpura, Hanamkonda, Andhra Pradesh, India.
  • SOUMYA. J ASWAQ AHMED Department of Biotechnology, Chaitanya Post Graduate College, Kishanpura, Hanamkonda, Andhra Pradesh, India.
  • RAJENDER. VADLURI Department of Biotechnology, Chaitanya Post Graduate College, Kishanpura, Hanamkonda, Andhra Pradesh, India.
  • RAJESH GOUD. GAJULA Department of Biotechnology, Chaitanya Post Graduate College, Kishanpura, Hanamkonda, Andhra Pradesh, India.

Keywords:

anti-oxidant, anti-bacterial, scavenging activity, susceptibility, anti-microbial agents

Abstract

The investigations were carried out to evaluate anti-oxidant and anti-bacterial activities, of stem methanol extract of vitex negundo at various concentrations. The methanol stem extract noticed significant scavenging activity on DPPH, superoxide, nitric oxide and hydrogen peroxide. The anti-bacterial activity was determined by agar diffusion well method using Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Salmonella paratyphi. The methanol stem extract exhibited significant inhibitory effect on all tested organisms. The highest susceptibility was noticed with bacillus subtilis. The phytochemical analysis revealed the presence of various phytochemicals viz., alkaloids, saponins, cardic glycosides etc., which play a vital role as anti-microbial agents.

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Published

31.03.2013

How to Cite

MURALI KRISHNA. T, MEENA. G, KAVYA. T, SOMESHWAR. C, SOUMYA. J ASWAQ AHMED, RAJENDER. VADLURI, & RAJESH GOUD. GAJULA. (2013). IN VITRO DETERMINATION OF ANTI-OXIDANT AND ANTI-BACTERIAL ACTIVITIES OF VITEX NEGUNDO LINN. International Journal of Pharma and Bio Sciences, 4(1), 121–127. Retrieved from https://ijpbs.net/index.php/journal/article/view/1898

Issue

Volume 4, Issue 1, 2013

Section

Research Articles

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