ASSESSMENT OF HORMONAL LEVELS IN TRAUMATIC HEAD INJURY

Abstract

Traumatic head injury (THI) is one of the main causes of death and disability in young adults with consequences ranging from physical disabilities to long term cognitive, behavioral, psychological and social defects. Acute THI leads to pituitary dysfunction. 80 patients were analyzed and divided according to the Glasgow coma scale into mild, moderate and severe categories .Medical history was obtained and a physical examination was performed. Age and sex was recorded of each patient. These patients were analyzed for their serum prolactin and serum testosterone levels. The study was conducted over of 18 months in the Goa Medical College. The standard deviation for prolactin was 7.24±1.19 for severe patients and 10.77 ± 2.2 for moderate patients and for testosterone it was 0.22± 0.03 for severe patients and 0.65±1.13 in moderate patient all of which are statistically significant. A statistically significant increase in serum prolactin levels and decrease in serum testosterone in patients of THI was observed.