EFFECTS OF EXTRACTION SOLVENTS ON CONCENTRATION OF VALERENIC ACID AND ANTIOXIDANT PROPERTY OF VALERIANA JATAMANSI JONES

Abstract

The effects of extracting solvents (dichloromethane, ethyl acetate and methanol) on the valerenic acid content and antioxidant activity of roots extracts of Valeriana jatamansi (cultivated and wild) were investigated. The tested plant extracts contained appreciable amounts of valerenic acid content which affects the antioxidant potential of plant extracts. Higher concentration of valerenic acid and antioxidant activity was obtained using dichloromethane, as compared to ethyl acetate and methanol. The results showed that the concentration of valerenic acid plays an important role in antioxidant activity of V. jatamansi. The concentration of valerenic acid was found in the order dichloromethane > ethyl acetate > methanol fractions in different samples of V. jatamansi. A similar trend was also found with antioxidant activity of the plant extracts.