Production Of Taxol By Pestalotiopsis Breviseta Cr01 Isolated From The Catharanceus Roceus And Its Growth Studies.

Authors

  • GOWRI KARTHIK Department of Biotechnology, Vels University, Pallavaram, Chennai–6OO 117, Tamilnadu, India
  • KATHIRAVANGOVINDARAJAN Department of Biotechnology, Vels University, Pallavaram, Chennai–6OO 117, Tamilnadu, India
  • SUKUMARAN NATARAJAPILLAI Department of Biotechnology, Vels University, Pallavaram, Chennai–6OO 117, Tamilnadu, India

Keywords:

Taxol, Pestalotiopsis breviseta, Catharanceus roceus, Coelomycetes

Abstract

As there is a continuous search for the alternative source for taxol, a million dollar drug due to its scarcity scientists have chosen microorganism as one of the alternate sources.Pestalotiopsis breviseta CR01 produces taxol invitro which was isolated from the plant Catharanceus roceus. The optimum growth of this fungus was analyzed by varying different growth parameters. The presence of taxol in this fungus was confirmed through HPTLC, UV and IR spectroscopic methods. The amount of taxol was quantified through HPLC analysis. This study reveals that Pestalotiopsis brevisetaCR01 optimum growth can be attained at temperature 25°C and pH 7.5 with the presence of dextrose as carbon source.

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Published

30.09.2012

How to Cite

GOWRI KARTHIK, KATHIRAVANGOVINDARAJAN, & SUKUMARAN NATARAJAPILLAI. (2012). Production Of Taxol By Pestalotiopsis Breviseta Cr01 Isolated From The Catharanceus Roceus And Its Growth Studies. International Journal of Pharma and Bio Sciences, 3(3), 1046–1053. Retrieved from https://ijpbs.net/index.php/journal/article/view/1639

Issue

Volume 3, Issue 3, 2012

Section

Research Articles

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