Protective Effects Of Garlic Extract Against Chromium Induced Genotoxicity In Bone Marrow Cells Of Mice

Authors

  • MOSHI RAJU M Human genetics lab, Department of zoology, Osmania University.
  • MINNY JAEL. P Human genetics lab, Department of zoology, Osmania University.
  • K. RUDRAMA DEVI Human genetics lab, Department of zoology, Osmania University.

Keywords:

chromium, chromosomal aberrations, protection, garlic extract.

Abstract

The protective effect of garlic extract in chromium induced genotoxicity was evaluated using analysis of chromosomal aberrations in somatic cells of mice in in vivo animal model. Three doses of garlic extracts were selected for modulation and administered to animals after priming with chromium all the animals were killed after 24 hrs of treatment and the mitotic preparations were made. A significant decrease was observed in the percentage of chromosomal aberrations when animals primed with garlic extract. The present results clearly indicate the protective nature of garlic extract against heavy metal genotoxicity.

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Published

30.09.2012

How to Cite

MOSHI RAJU M, MINNY JAEL. P, & K. RUDRAMA DEVI. (2012). Protective Effects Of Garlic Extract Against Chromium Induced Genotoxicity In Bone Marrow Cells Of Mice. International Journal of Pharma and Bio Sciences, 3(3), 839–847. Retrieved from https://ijpbs.net/index.php/journal/article/view/1618

Issue

Volume 3, Issue 3, 2012

Section

Research Articles

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