Antimicrobial Activities Of Avicennia Marina, Caesalpinia Pulcherrima And Melastoma Malabathricum Against Clinical Pathogens Isolated From Uti.

Abstract

The ethnobotanical efficacy of Indian Medicinal plants leaves of Avicennia marina, Caesalpinia Pulcherrima and Melastoma Malabathricum was evaluated against Gram positive (Staphylococcus aureus,) and Gram-negative (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa) bacteria. Leaves were extracted using different solvents such as hexane, chloroform, ethyl acetate and methanol by soxhlet extraction method. The antibacterial activity was evaluated using agar well diffusion method. The plant extracts showed antibacterial activity against the four bacterial species taken in the present investigation. Among treatments, maximum invitro inhibition was scored in the extract of the plant Avicennia marina followed by Caesalpinia Pulcherrima and Melastoma Malabathricum. All plant extracts showed significant zone of inhibition for Staphylococcus aureus than for other bacterial species taken for the study. Among the four solvents tested the methanol and ethyl acetate extracts were more potent in their antibacterial activity. Preliminary phytochemical screening was also done for the leaves extract of Avicennia marina, Caesalpinia Pulcherrima and Melastoma Malabathricum. The results obtained in the present study shows that Avicennia marina, Caesalpinia pulcherrima and Melastoma Malabathricum can be used in treating diseases caused by the test organisms.