SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME CHALCONES AND FLAVONES HAVING 2-HYDROXY ACETOPHENONE MOIETY.

Authors

  • NITIN G. GHODILE Vidya Bharati Mahavidyalaya, Amravati.Amravati, Maharastra 444602.
  • P. R. RAJPUT Vidya Bharati Mahavidyalaya, Amravati.Amravati, Maharastra 444602.
  • V. W. BANEWAR Govt. Vidarbha Institute of Science and Humanities, Amravati, Maharastra 444602.
  • A. R. RAUT Govt. Vidarbha Institute of Science and Humanities, Amravati, Maharastra 444602.

Keywords:

2-Hydroxy acetophenone, 2-Hydroxy chalcones, Flavones, Antifungal and Antibacterial activity.

Abstract

Chalcones (3a-e) on reaction with catalytic amount of I2 in DMSO gives Flavones (4a-e) in high yield. The corresponding chalcones (3a-e) were obtained by Claisen-Schimdt condensation of aromatic aldehydes with o-hydroxy acetophenone. The flavones obtained were further studied for antifungal activity.  

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Published

30.09.2012

How to Cite

NITIN G. GHODILE, P. R. RAJPUT, V. W. BANEWAR, & A. R. RAUT. (2012). SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME CHALCONES AND FLAVONES HAVING 2-HYDROXY ACETOPHENONE MOIETY. International Journal of Pharma and Bio Sciences, 3(3), 389–395. Retrieved from https://ijpbs.net/index.php/journal/article/view/1496

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Research Articles

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