An Invitro Evaluation Of Cytotoxic Activity Of Sophora Interrupta

Authors

  • T. VITHYA Dayanandasagar College of Pharmacy, Bangalore
  • DR.V.KAVIMANI Mother Theresa College of pharmacy, Pondicherry
  • K.ALHASJAJIJU Strides Arcolab Ltd, Bangalore
  • B.RAJKAPOOR Dayanandasagar College of Pharmacy, Bangalore
  • B.K.SAVITHA Dayanandasagar College of Pharmacy, Bangalore

Keywords:

Sophora interrupta, MTT assay, HeLa, HePG2, Cytotoxicity

Abstract

In this study we evaluated the cytotoxicity activity of Sophora interrupta. For evaluation HeLa and HePG2 cell lines were treated with the various concentrations of Methanolic extract. The result showed an IC50 value of 211.5µg/ml and158.2µg/ml respectively in HeLa and HePG2 cell lines. The MTT assay results confirmed the cytotoxicity of the plant. Further, molecular characterisation studies and in vivo studies recommended to confirm still the anticancer activity of this plant.

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Published

30.06.2012

How to Cite

T. VITHYA, DR.V.KAVIMANI, K.ALHASJAJIJU, B.RAJKAPOOR, & B.K.SAVITHA. (2012). An Invitro Evaluation Of Cytotoxic Activity Of Sophora Interrupta. International Journal of Pharma and Bio Sciences, 3(2), 420–425. Retrieved from https://ijpbs.net/index.php/journal/article/view/1352

Issue

Volume 3, Issue 2, 2012

Section

Research Articles

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