Evaluation Of Toothache Activity Of Methanolic Extract And Its Various Fractions From The Leaves Psidium Guajava Linn

Authors

  • S. JAYAKUMARI Department of Pharmacognosy School of Pharmaceutical Sciences, (VISTAS) Vel’s University, Pallavaram, Chennai-600117, India
  • J. ANBU Department of Pharmacology and Toxicology, School of Pharmaceutical Sciences, (VISTAS) Vel’s University, Pallavaram, Chennai-600117, India
  • V. RAVICHANDIRAN Department of Pharmacognosy School of Pharmaceutical Sciences, (VISTAS) Vel’s University, Pallavaram, Chennai-600117, India
  • S.NITHYA Department of Pharmacology and Toxicology, School of Pharmaceutical Sciences, (VISTAS) Vel’s University, Pallavaram, Chennai-600117, India
  • ASHWINI ANJANA Department of Pharmacology and Toxicology, School of Pharmaceutical Sciences, (VISTAS) Vel’s University, Pallavaram, Chennai-600117, India
  • D. SUDHARANI Department of Pharmacognosy School of Pharmaceutical Sciences, (VISTAS) Vel’s University, Pallavaram, Chennai-600117, India

Keywords:

Psidium guajava L, analgesic, anti-inflammatory, anti-microbial, Toothache

Abstract

Psidium guajava L is commonly known as guava in English. The present investigation focuses on the toothache activity. The investigation is based upon the analgesic, anti-inflammatory and anti-microbial activity of water extract of Psidium guajava L.  The study assessed the different solvent extracts of Psidium guajava leaf for thin layer chromatography (TLC) and also evaluated the analgesic activity by Hot plate and acetic acid induced writhing, anti-inflammatory action by Invitro HRBC membrane stabilization method and antimicrobial activity by Disc diffusion method, Agar well diffusion method and Minimum inhibitory concentrations (MIC) in animal model. The present preliminary study demonstrated marked toothache activity of Psidium guajava leaf. These results support the notion that plant flavonoids and extracts may have  many roles as pharmaceuticals.

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Published

30.06.2012

How to Cite

S. JAYAKUMARI, J. ANBU, V. RAVICHANDIRAN, S.NITHYA, ASHWINI ANJANA, & D. SUDHARANI. (2012). Evaluation Of Toothache Activity Of Methanolic Extract And Its Various Fractions From The Leaves Psidium Guajava Linn. International Journal of Pharma and Bio Sciences, 3(2), 238–249. Retrieved from https://ijpbs.net/index.php/journal/article/view/1331

Issue

Volume 3, Issue 2, 2012

Section

Research Articles

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