Analgesic Effect Of Neem (Azadirachta Indica) Seed Oil On Albino Rats

Authors

  • SANJAY KUMAR Assoc. Prof., Dept. of Pharmacology, IMS & SUM Hospital, SOA University, Bhubaneswar, India
  • DIVYA AGRAWAL Asst. Prof., Dept. of Anatomy, IMS & SUM Hospital, SOA University, Bhubaneswar, India
  • JYOTSNA PATNAIK Professor, Dept. of Pharmacology, IMS & SUM Hospital, SOA University, Bhubaneswar, India
  • SHANTILATA PATNAIK Professor, Dept. of Pharmacology, IMS & SUM Hospital, SOA University, Bhubaneswar, India

Keywords:

Analgesic, Neem Seed Oil, Tail flick latency, Morphine

Abstract

Neem (Azadirachta indica), an indigenous plant is reported to have antidiabetic, anti-inflammatory, antifungal and several other medicinal properties. The present work is undertaken to study the analgesic activity of neem seed oil on albino rats. Neem seed oil was obtained in pure form from Indian Herbs Research Supply Company Limited, Saharanpur, UP.  The analgesic activity was tested by the tail flick method using the analgesiometer (Techno.). Neem seed oil in the doses of 0.25, 0.5, 1 and 2 ml/kg body weight was given intraperitoneally to different group of rats. Tail flick latency was measured in seconds before and after the drug injection. Results were compared with morphine and statistically analysed. Neem seed oil showed significant  analgesic effect in  the dose of 1 and 2 ml/kg. Neem seed oil has dose-dependent analgesic activity.

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Published

30.06.2012

How to Cite

SANJAY KUMAR, DIVYA AGRAWAL, JYOTSNA PATNAIK, & SHANTILATA PATNAIK. (2012). Analgesic Effect Of Neem (Azadirachta Indica) Seed Oil On Albino Rats. International Journal of Pharma and Bio Sciences, 3(2), 222–225. Retrieved from https://ijpbs.net/index.php/journal/article/view/1328

Issue

Volume 3, Issue 2, 2012

Section

Research Articles

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