COMPARATIVE PHYTOCHEMICAL AND PHARMACOLOGICAL SCREENING OF THE METHANOLIC EXTRACTS OF THE FRONTAL AND MATURE LEAVES OF TECTONA GRANDIS.

Authors

  • NAIRA NAYEEM Department of Pharmaceutical chemistry, Krupanidhi College of Pharmacy
  • KARVEKAR MD Department of Pharmaceutical chemistry, Krupanidhi College of Pharmacy

Keywords:

Flavonoid, phenolic acid, Tectona grandis, wound healing.

Abstract

The ethnopharmacological survey has revealed that only the frontal leaves of Tectona grandis have
been used for the treatment of wounds. Comparative study of the activity and phytoconstituents of the
mature and the frontal leaves of Tectona grandis was carried out. Wound healing activity of both the
extracts was evaluated by the excision wound model. The wound healing was 100 % on the 12th day
and 16th day in the frontal leaves (P<0.001) and the mature leaves (P<0.05) respectively which was
quite significant. A comparative phytochemical analysis was carried out to prove that the amount of
phytoconstituents varied with the stages of development of the plants which in turn may be contributing
to the activity of the extract. Total phenolic acid and flavonoid content of both the extracts was
estimated and was found to be more in the frontal leaf extract, giving scientific proof to the use of frontal
leaves.

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Published

30.09.2010

How to Cite

NAIRA NAYEEM, & KARVEKAR MD. (2010). COMPARATIVE PHYTOCHEMICAL AND PHARMACOLOGICAL SCREENING OF THE METHANOLIC EXTRACTS OF THE FRONTAL AND MATURE LEAVES OF TECTONA GRANDIS. International Journal of Pharma and Bio Sciences, 1(3), 1–7. Retrieved from https://ijpbs.net/index.php/journal/article/view/122

Issue

Volume 1, Issue 3, 2010

Section

Research Articles