Exploring Biological Networks For Finding Potential Drug Targets In Methicillin Resistant Staphylococcus Aureus

Abstract

Methicillin resistant Staphylococcus aureus (MRSA) has emerged as a dreadful pathogen causing broad range of infections. The complexity in treating these pathogens corresponds to the alarming increase and spread of resistance against antibiotics. Thus the search for novel antimicrobials targeting towards new drug targets becomes indispensable for combating such resistant pathogens. The present study focuses on exploring the essential bacterial pathways of MRSA for the identification of promisable drug targets with the aid of metabolic pathway analysis and choke point analysis. The present work thus paves the way for treating MRSA with new antimicrobials targeted towards the identified promisable drug targets.