Lectin Based Hemagglutination Assay: A Screening Test For Thyroid Disorders

Authors

  • DHIRAJ TRIVEDI Department of Biochemistry, SDM College of Med. Sci and Hosp, Dharwad, Karnataka
  • CHHAYA TRIVEDI Department of Biochemistry, DY patil Medical College, Kolhapur Maharashtra.
  • PRAMOD KAMBLE Department of Biochemistry, SDM College of Med. Sci and Hosp, Dharwad, Karnataka
  • MC CHANDRU Department of Biochemistry, Karnataka Institute of Medical Sciences, Hubli, Karnataka

Keywords:

Lectin, Hemagglutination, Glycoprotein

Abstract

The Present study demonstrates the diagnostic characteristics of Pedilanthus tithymoloides, agglutinin (PTA), lectin based hemagglutination method for screening of thyroid disorders as compared with RIA as gold standard. The result estimates 90% sensitivity, 95.55% specificity and 92.63% observed agreement with RIA test in thyroid disorders. The result of hyperthyroidism, hypothyroidism and cretinism are discussed and these results project Lectin based hemagglutination as simple, reliable, cost effective and an alternative method of choice for screening of thyroid disorders.

Published

31.12.2011

How to Cite

DHIRAJ TRIVEDI, CHHAYA TRIVEDI, PRAMOD KAMBLE, & MC CHANDRU. (2011). Lectin Based Hemagglutination Assay: A Screening Test For Thyroid Disorders. International Journal of Pharma and Bio Sciences, 2(4), 576–780. Retrieved from https://ijpbs.net/index.php/journal/article/view/1126

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Section

Research Articles

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