UV-Spectrophotometric Determination of Tenatoprazole from its Bulk and Tablets

Authors

  • M. SUGUMARAN Department of Pharmaceutical Analysis, Adhiparasakthi College of Pharmacy, Melmaruvathur- 603319,Tamilnadu,India.
  • R.NAGESWARA RAO Department of Pharmaceutical Analysis, Adhiparasakthi College of Pharmacy, Melmaruvathur- 603319,Tamilnadu,India.
  • D. JOTHIESWARI Department of Pharmaceutical Analysis, Adhiparasakthi College of Pharmacy, Melmaruvathur- 603319,Tamilnadu,India.

Keywords:

Tenatoprazole, UV-spectrophotometric method, Tablet formulation and Validation

Abstract

A simple , rapid, sensitive and accurate UV-spectrophotometric method has been developed for estimation of Tenatoprazole from Pharmaceutical formulation. In 0.1N NaOH, Tenatoprazole showed absorbance maxima at 314nm. Linearity was observed in the concentration range of 2-12 µg/ml (r2 =0.999).The amount of drug estimated from the formulation was found to be in the good agreement with label claim. The recovery studies were carried out at three different levels i.e. at 50%100% and 125%. The method was validated statistically.

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Published

31.03.2010

How to Cite

M. SUGUMARAN, R.NAGESWARA RAO, & D. JOTHIESWARI. (2010). UV-Spectrophotometric Determination of Tenatoprazole from its Bulk and Tablets. International Journal of Pharma and Bio Sciences, 1(1), 1–6. Retrieved from https://ijpbs.net/index.php/journal/article/view/107

Issue

Volume 1, Issue 1, 2010

Section

Research Articles