Evaluation Of Anti Implantation And Abortificient Properties Of Portulaca Oleracea L. In Albino Rats

Abstract

The present study was aimed to evaluate the effect of Portulaca oleracea L on fertility of female albino rats.  Albino rats were orally administered with Petroleum Ether, chloroform and Ethanol crude extracts of aerial part of Portulaca oleracea L in both high and low dose (500mg and 250 mg / kg of body weight / day, for 7 days), and effect of crude extract on Anti implantation and Abortificient activity was investigated.  The treatment of petroleum ether crude extract has shown 20% and 30% reduction in implantation activity at low (250) and (500) high doses respectively.  In case of chloroform and Ethanol crude extracts, the  chloroform extract  has shown 50% and 60% reduction in implantation activity at low and high doses respectively, whereas Ethanolic crude extracts have shown 40% and 50% reduction in implantation sites with  respect to low and high dose of extract treatment .   Ethanolic crude extract treatment has shown abortificient activity but the   petroleum ether and chloroform extract treatment to pregnant rats did not shown any abortificient activity.