Synthesis And Evaluation Of New 3- Substituted-[3, 4-Dihydro Pyrimidinones]-Indolin-2-Ones For Anti Inflammatory Activity

Authors

  • M. AJITHA Center for Pharmaceutical Sciences, IST, JNTU, Kukatpally, Hyderabad- 500085 , India
  • K. RAJNARAYANA Glukem Pharmaceutical (P) Ltd, IDA, Phase II, Cherlapally, Hyderabad -500052, India

Keywords:

Dihydropyrimidinones, Indole-2-ones, Anti-inflammatory activity

Abstract

New 3-substituted [3, 4-dihydropyrimidinones]-Indolin-2-ones have been synthesized and tested for Anti-inflammatory activity by caragenen induced rat paw method. Among them compounds AJ16, AJ15, AJ14, AJ13 and AJ12 exhibited higher anti inflammatory activity. However, these anti-inflammatory activities are lower than standard Diclofenac Sodium.

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Published

31.12.2011

How to Cite

M. AJITHA, & K. RAJNARAYANA. (2011). Synthesis And Evaluation Of New 3- Substituted-[3, 4-Dihydro Pyrimidinones]-Indolin-2-Ones For Anti Inflammatory Activity. International Journal of Pharma and Bio Sciences, 2(4), 81–90. Retrieved from https://ijpbs.net/index.php/journal/article/view/1002

Issue

Volume 2, Issue 4, 2011

Section

Research Articles

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