<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 2 Issue 2</issue_number>
<issue_period>2011 (April - June) </issue_period>
<title>Ameliorative Action Of Nigella Sativa Against Iron Induced Chromosomal Aberrations In Rat Bone Marrow Cells In Vivo</title>
<abstract>Iron deficiency is a worldwide problem and is, in general, more frequent than its excess.  lessThan i greaterThan Nigella sativa lessThan /i greaterThan  may also act as an ROS scavenger and as a metal chelant. To examine these possibilities, we tested  lessThan i greaterThan in vivo lessThan /i greaterThan  the effect of  lessThan i greaterThan Nigella sativa lessThan /i greaterThan  (50 mg/kg b.wt.) against the genotoxicity of FeSO lessThan sub greaterThan 4. lessThan /sub greaterThan 7H lessThan sub greaterThan 2 lessThan /sub greaterThan O. Bone marrow cells were obtained from the rats using the technique described by Preston  lessThan i greaterThan et al lessThan /i greaterThan . (1987). The results of treatments with  lessThan i greaterThan Nigella sativa  lessThan /i greaterThan indicated that it statistically significantly decreases the number of with aberrations induced by FeSO lessThan sub greaterThan 4. lessThan /sub greaterThan 7H lessThan sub greaterThan 2 lessThan /sub greaterThan O, but it cannot completely protect cells from damage.  lessThan i greaterThan Nigella sativa lessThan /i greaterThan  showed the most efficient anticlastogenic effect during simultaneous treatment with FeSO lessThan sub greaterThan 4. lessThan /sub greaterThan 7H lessThan sub greaterThan 2 lessThan /sub greaterThan O. The result further strengthened the findings about the protective and antigenotoxic properties of  lessThan i greaterThan Nigella sativa lessThan /i greaterThan .</abstract>
<authors>Nuzhat Parveen And G. G. H. A. Shadab</authors>
<keywords>Nigella sativa; Chromosomal aberrations; Ferrous sulfate; Genotoxicity.</keywords>
<pages>470-477</pages>
</article>
</Journal>
