International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 2 Issue 2
2011 (April - June)
Antimicrobial Evaluation And Phytochemical Analysis Of A Known Medicinal Plant Samanea Saman (Jacq.) Merr. Against Some Human And Plant Pathogenic Bacteria And Fungi
The present investigations evaluate the antimicrobial efficacy of six different solvent extracts and isolated constituents of lessThan i greaterThan Samanea saman lessThan /i greaterThan (Jacq.) Merr. against 21 microorganisms. Our result revealed that, the methanol extract showed a highest antibacterial activity with zone of inhibition ranging from 11.0mm to 30.5mm at 1mg/ml concentration. The MIC value of the methanol extract for the tested bacteria ranged between 15µg/ml to 500µg/ml. The most susceptible organism in the present investigation was lessThan i greaterThan Streptococcus faecalis lessThan /i greaterThan (MIC 15µg/ml) followed by lessThan i greaterThan Staphylococcus aureus lessThan /i greaterThan (MIC 62µg/ml), while the most resistant was lessThan i greaterThan Proteus vulgaris lessThan /i greaterThan (MIC 500µg/ml). The highly significant antifungal activity against all the fungi was observed in methanol extract with percentage of inhibition ranging from 20.4% to 81.6% depending upon fungal species at 1mg/ml concentration. The IC lessThan sub greaterThan 50 lessThan /sub greaterThan value of the methanol extract ranged from 0.3mg/ml to 5mg/ml. Among the tested fungi, lessThan i greaterThan Fusarium moniliforme lessThan /i greaterThan (IC lessThan sub greaterThan 50 lessThan /sub greaterThan 0.3mg/ml) was highly sensitive and lessThan i greaterThan Aspergillus tamari lessThan /i greaterThan (IC lessThan sub greaterThan 50 lessThan /sub greaterThan 5mg/ml) was least sensitive.
Thippeswamy S.,Praveen P.,Mohana D. C. And Manjunath K.
Samanea saman, antimicrobial activity, human pathogenic bacteria, seed-borne fungi, active fraction.
443-451