10.22376/ijpbs.2019.10.1.p1-12 Volume 13 Issue 1 January - March Phytochemical compounds obtained from the medicinal plants have effective therapeutic applications both in the pure form of compounds or as standardized extracts. So far, these compounds are not evaluated scientifically or used to their best potential and demand detailed studies. Thus, the present study emphasis screening of phytochemicals and the antimicrobial properties of lessThan i greaterThan Tecoma capensis lessThan /i greaterThan belonging to the family-Bignoniaceae and lessThan i greaterThan Alstonia scholaris lessThan /i greaterThan which belongs to the family-Apocyanaceae. The crude plant powder and stem bark powder extracts were considered for the analysis. All the three solvents of stem bark extracts were tested against two gram positive bacteria ( lessThan i greaterThan Bacillus subtilis lessThan /i greaterThan and lessThan i greaterThan Staphylococcus aureus lessThan /i greaterThan ) and two gram negative bacteria ( lessThan i greaterThan Salmonella typhi lessThan /i greaterThan and lessThan i greaterThan Escherichia coli lessThan /i greaterThan ) using sterile disk method. Ethanol extracts of lessThan i greaterThan Tecoma lessThan /i greaterThan capensis and lessThan i greaterThan Alstonia scholari lessThan /i greaterThan s showed the highest inhibition zone (8 mm) and lowest inhibition zone (4mm) was found in aqueous and methanol extracts. The preliminary phytochemical screening showed the presence of alkaloids, saponins, flavonoids, tannins and phenols. Based on our analysis, we conclude that due to the potential to fight against human disease caused by some microbial pathogens, these plant extracts can be used to discover the bioactive compounds which may leads for the development of new pharmaceutical research studies. Niranjan M H and Prabhurajeshwar Tecoma capensis, Alstoniascholaris, phytochemical screening, Antimicrobial activity, Antibiotics, Extracts 60-70