International Journal of Pharma and Bio Sciences
ijpbs.net
editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 12 Issue 3
2021 (July-September)
Oral Probiotics Containing Streptococcus Salivarius M18 for the Prevention of Dental Plaque: A Systematic Review
Oral commensal probiotic lessThan i greaterThan Streptococcus salivarius lessThan /i greaterThan M18 has been recognised to offer potential benefit in oro-dental health, due to its ability to colonise the oral cavity and ward off pathogens implicated in microbial dysbiosis causing oral and dental ailment such as dental plaque. The aim of this systematic review was to search and analyse the published literature on orally targeted lessThan i greaterThan Streptococcus salivarius lessThan /i greaterThan probiotic strain M18 and its effects to manage dental hygiene. The research questions were formulated according to the PICO strategy probiotic intervention for the prevention of dental plaque. A broad search for published articles was carried out using the electronic databases MEDLINE through PubMed, SciFinder and Web of Science by two independent reviewers. The quality of the studies was assessed using the JADAD scale and the risk of bias was assessed according to the Cochrane Collaboration assessment tool. Of the 323 published articles related to lessThan i greaterThan S. salivarius lessThan /i greaterThan M18 identified by the database search, 3 studies with relevance to dental plaque were included in this review. Studies with lessThan i greaterThan S. salivarius lessThan /i greaterThan M18 showed significant reduction in dental plaque with longer treatment duration. Most studies included in this review highlighted the potential of lessThan i greaterThan S. salivarius lessThan /i greaterThan M18 probiotics to reduce the dental plaque score in humans. Modifying the administration protocol and duration of probiotic therapy may further extend the benefits of probiotic therapy.
Marte Eva Koelemaij John David Francis Hale and Rohit Jain
Dental plaque, oral health, periodontal diseases, dental caries, probiotics, Streptococcus salivarius M18, BLIS M18TM
43-49