10.22376/ijpbs.2019.10.1.p1-12 Volume 12 Issue 1 2021 (January-March) Type 2 diabetes mellitus (T2DM) is a chronic disorder and has a high prevalence rate in developing countries and in populations undergoing "westernization" or "modernization". Intracellular magnesium plays a key role in insulin-mediated-glucose-uptake. We planned this study with the purpose to find the correlation between magnesium and glycated haemoglobin lessThan b greaterThan lessThan /b greaterThan levels in controlled and uncontrolled type 2 diabetes mellitus in premenopausal women. In the present observational study, 210 premenopausal women patients were divided into three groups: group I includes 70 normal healthy premenopausal women (HbA1c lessThan 5.7%) as controls, Group II includes 70 controlled diabetic patients without complications (HbA1c lessThan 7%) and group III includes 70 uncontrolled diabetic patients without complications (HbA1c ≥7%) and were matched by age. The mean glycated hemoglobin (HbA1c) was 4.0 ± 0.4 % in healthy controls, 6.3 ± 0.78 % in controlled DM group and 10.67 ± 2.0 % in uncontrolled DM group. Mean serum magnesium levels were 1.56 ± 0.18 mg/dL in controlled DM group and 1.35 ± 0.30 mg/dL in uncontrolled DM group. It showed a significant reduction in the mean of the plasma levels of magnesium in diabetic groups when compared with the control group (p lessThan 0.05). There was an also strong negative correlation between the plasma levels of magnesium and HbA lessThan sub greaterThan 1C lessThan /sub greaterThan  levels (r = -0.100, p=0.003) in diabetic premenopausal patients. Thus, our study concludes that hypomagnesemia is associated with poor glycaemic control in premenopausal women. Large-scale randomized clinical trials are required in order to determine whether the correction of Mg lessThan sup greaterThan 2+ lessThan /sup greaterThan deficiency improves the glycaemic control. Maninder Kansal, Kirti, Sumit Kumar and Suraj Kumar Type 2 diabetes mellitus, magnesium levels, Fasting blood glucose, Glycated haemoglobin, HbA1c, Premenopausal women. 104-107