10.22376/ijpbs.2019.10.1.p1-12 Volume 2 Issue 2 2011 (April - June) lessThan i greaterThan Annona cherimola lessThan /i greaterThan is believed indigenous to South Central America and also found in some parts of Asia. An attempt is made to evaluate the anti inflammatory and antioxidant activites of lessThan i greaterThan Annona cherimola lessThan /i greaterThan leaf extract as the denaturation of proteins and free radical damage or oxidative stress are inter-linked and influence each other. lessThan i greaterThan Invitro lessThan /i greaterThan anti inflammatory and antioxidant properties were tested on hexane and methanolic leaf extracts of lessThan i greaterThan Annona cherimola lessThan /i greaterThan by means of anti denaturation of bovine serum albumin and reducing antioxidant power respectively. In anti denaturation study it was observed that methanolic extract showed greater percentage of inhibition of bovine serum albumin denaturation i.e 77.6% where as hexane extract showed 63.5% at the lowest concentration respectively. In case of antioxidant screening also, methanolic extract showed better reducing antioxidant power compared to hexane extract dose dependently. Thus the results indicate that methanolic extract of lessThan i greaterThan Annona cherimola lessThan /i greaterThan was found to possess significantly good anti inflammatory and antioxidant activities and this can be attributed to the presence of phenolic compounds Adarsh Verma M.,Ajay Kumar P.,Kavitha D. And Anurag K. B. Annona cherimola, Anti denaturation, Reducing antioxidant power 1-6