<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 11 Issue 2</issue_number>
<issue_period>2020 (April-June)</issue_period>
<title><b>Investigation of Pharmacological Activities of Fenugreek Seeds </b><b>Extracts of Different Solvents</b></title>
<abstract>Fenugreek plant was used since ancient time in Indian food for various reasons and its seeds were used due to some medicinal issues in the treatment of various types of disease like in pains, in fungal infections and to lower the blood glucose level due to it's bitter in taste. The data obtained in past study regarding the presence of phytochemical components will serve as a valuable tool for various pharmacological activities of the test compound. Usually those spices include the fenugreek seeds and its leaf which were used in making the food have the medicinal properties and all provide the protection against most of disease. This plant and its product posses very important medicinal characters like lower the blood glucose level, lower the blood pressure, sometimes it was used as an emetics in case of poisoning. Due to all these property it has a good value in Indian spices. When a condition in which decreased platelet count called as thrombocytopenia. Thrombocytopenic disorders (dengue, chikungunya, malaria etc.) are spreading in urban areas with lightning speed. This is now endemic in more than 125 countries. The major mechanisms for a reduced platelet count are suppress the red bone marrow in which the production of platelets take place and increased destruction of platelets. Use of extract of fenugreek seeds for different pharmacological actions has been described by many scientists. The proposed research work explores various solvent extracts of fenugreek seeds for increase in platelet count in induced thrombocytopenic experimental animals and to study various pharmacological activities e.g- Hepatoprotective ,antioxidant activity, hematology test (blood clotting time). So seeds of fenugreek were soaked with n-hexane, acetone, ethanol water and carbon tetrachloride using Soxhlet apparatus and distilled water using maceration for 8 hours and experiments on experimental animals to see increase in platelet count carried out. Hematological studies on experimental animals may prove beneficial for toxicologists.</abstract>
<authors>Prashant Raghav, Dr.Danish Ahmed and Dr.Vikas Kumar</authors>
<keywords>Trigonella foenum graecum, Thrombocytopenia, antidiabetic, hypocholesterolemic, hypoglycemic, anticarcinogenic.</keywords>
<pages>40-45</pages>
</article>
</Journal>
