10.22376/ijpbs.2019.10.1.p1-12 Volume 10 Issue 4 2019 (October-December) Ethnobotanical reports suggested the presence of several numbers of medicinally important plant-species from all over the world containing a high degree of curative properties against pathogens. The current onus is on researching and developing new antimicrobial agents from various sources to combat microbial resistance build up among pathogens. The current investigation is on the antimicrobial properties of the endangered medicinal plants chosen from the region of Karnataka, India. project investigations have been carried out to test the presence of the antimicrobial compounds present in the parts of the following plants - lessThan i greaterThan Janakia arayalpathra , Artocarpus hirsutus lessThan /i greaterThan , lessThan i greaterThan Calophyllum apetalum lessThan /i greaterThan Wild., lessThan i greaterThan Terminalia orenulata lessThan /i greaterThan , lessThan i greaterThan Dorstenia indica lessThan /i greaterThan and lessThan i greaterThan Vernonia amygdalina lessThan /i greaterThan . The dried extracts of flowers, leaves and stem of the endangered plants were analysed for their antimicrobial properties using well diffusion method and the minimum inhibitory concentration (MIC) of the extracts showing positive inhibitory activity against pathogens like lessThan i greaterThan E. coli, E. faecalis, S. aureus lessThan /i greaterThan and lessThan i greaterThan K. pneumoniae lessThan /i greaterThan . The results indicated that the plant flower, leaf and stem extract of lessThan i greaterThan Vernonia amygdalina possess lessThan /i greaterThan antimicrobial property with a zone of inhibition measuring lessThan i greaterThan   lessThan /i greaterThan 7 to 10 mm against lessThan i greaterThan E.coli lessThan /i greaterThan and lessThan i greaterThan E.faecalis lessThan /i greaterThan . The plant Wild jack or lessThan i greaterThan Artocarpus lessThan /i greaterThan lessThan i greaterThan hirsutus lessThan /i greaterThan showed antimicrobial property which were restricted to its stem extract against lessThan i greaterThan E. faecalis lessThan /i greaterThan only. While lessThan i greaterThan Janakia arayalparthra lessThan /i greaterThan showed a positive antimicrobial activity against lessThan i greaterThan S. aureus lessThan /i greaterThan only. VANI L AND DR. M.JAYARAMU Endangered plants, plant extracts, antimicrobial, well-diffusion, Minimum inhibitory concentration 142-149