10.22376/ijpbs.2019.10.1.p1-12 Volume 10 Issue 2 2019 (April-June) Mosquitoes are an important public health concern as they spread life-threatening diseases such as malaria, filaria, Japanese encephalitis, dengue fever, chikungunya, and yellow fever. In the last decades, synthetic insecticides were extensively used for the control of these vector-borne diseases but it also reported the detrimental side-effects in human beings and pet animals. To overcome the side effects, plants-derived secondary metabolites were screened and tested for insecticidal properties. Plant-derived agents belonging to many families have been reported to possess larvicidal properties against lessThan i greaterThan Cx. quenquifasciatus lessThan /i greaterThan , lessThan i greaterThan Ae. aegypti lessThan /i greaterThan and lessThan i greaterThan An. stephensi lessThan /i greaterThan mosquitoes (Diptera: Culicidae). Larvicidal agents for mosquito larval control are a major module for controlling vector-borne diseases. The present study deals with the insecticidal activity of ethanol extracts of lessThan i greaterThan Cassava lessThan /i greaterThan leaves against lessThan i greaterThan Culex quinquefasciatus, lessThan /i greaterThan lessThan i greaterThan Aedes aegypti, lessThan /i greaterThan and lessThan i greaterThan Anopheles stephensi lessThan /i greaterThan , lessThan i greaterThan lessThan /i greaterThan larvae. Result analysis clearly indicates that ethanol extract of lessThan i greaterThan Cassava lessThan /i greaterThan showed higher potency against lessThan i greaterThan Cx. quinquefaciatus lessThan /i greaterThan and lessThan i greaterThan Ae. aegypti lessThan /i greaterThan as compared to lessThan i greaterThan An. stephensi lessThan /i greaterThan . The phytochemicals or crude extracts derived from plant sources also act as a larvicide against mosquito vectors. The ethanolic extract was found potent Ethanol extract were found significantly lethal to the tested mosquito vectors. The study clearly revealed that lessThan i greaterThan lessThan /i greaterThan Crude extract or isolated bioactive compounds from the plant Cassava could be used in breeding grounds of the mosquitoes and can be used as an alternative against synthetic insecticides lessThan i greaterThan . lessThan /i greaterThan VINITA VINJOY JERUSHA AND ARULSAMY JEBANESAN Larvicidal activity, secondary metabolite, Cassava, ethanol extract, mosquito vectors, bioactive compounds. 113-117