<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 9 Issue 3</issue_number>
<issue_period>2018 (July-September)</issue_period>
<title><b>Mosquitocidal efficacies of the medicinal plant senna alata Methanolic leaf extract against dengue and zika virus Vector aedes aegypti.</b></title>
<abstract>Mosquito-borne diseases such as dengue, yellow fever, chikungunya and zika fever are among the leading causes of deaths world-wide.  lessThan i greaterThan Aedes aegypti  lessThan /i greaterThan is a primary vector of dengue fever and There is no effective vaccine and treatment against dengue, chikungunya and zika fever; therefore the only way to reduce these diseases is mosquito control. The development of resistance in mosquitoes to most synthetic insecticides and repellents calls for the search for alternatives from plant origin. The present study explored the effects of  lessThan i greaterThan Senna alata  lessThan /i greaterThan methanolic leaf extract on larvicidal, pupicidal, ovicidal and ovipositional deterrence against dengue and zika virus vector  lessThan i greaterThan Ae. aegypti. lessThan /i greaterThan  Phytochemical and GC-MS analysis of the plant extract were carried out. Bioassay test was conducted for testing the efficacy of methanolic leaf extract of  lessThan i greaterThan S. alata  lessThan /i greaterThan on  lessThan i greaterThan Ae. aegypti  lessThan /i greaterThan at different stages of development. The effect of methanolic extract  lessThan i greaterThan S. alata  lessThan /i greaterThan on the hatchability of  lessThan i greaterThan Ae.aegypti  lessThan /i greaterThan eggs was determined. Hatching rate was calculated on the basis of non-hatchability of eggs. The effect of methanolic extract  lessThan i greaterThan S. alata  lessThan /i greaterThan on oviposition of  lessThan i greaterThan Ae. aegypti  lessThan /i greaterThan was determined under choice and no-choice oviposition test. Considerably low LC lessThan sub greaterThan 50 lessThan /sub greaterThan  /24 hours values of methanolic leaf extract  lessThan i greaterThan S.alata  lessThan /i greaterThan against different instar (I, II, III, IV and pupae) stages of  lessThan i greaterThan Ae. aegypti lessThan /i greaterThan  obtained during the present study proved the larvicidal, pupicidal property of the plant. Young larvae were found to be relatively more susceptible than the older ones.The hatchability of  lessThan i greaterThan Ae. aegypti lessThan /i greaterThan  eggs was decreased when placed in media of methanolic leaf extract. The reduction in percent hatch was inversely proportional to the concentration of methanolic leaf extract. Oviposition Active Index and Oviposition Deterrent Index indicated a low preference of  lessThan i greaterThan Ae. aegypti lessThan /i greaterThan  to methanolic leaf extract treated medium for egg laying. In conclusion, this study recommends that the methanolic leaf extract of  lessThan i greaterThan S.alata lessThan /i greaterThan  could be used as an alternative method in the Dengue and Zika virus vector management programs.</abstract>
<authors>KARTHIYAYNI.N , PRAVIN. Y, PALANIKUMAR. M, MOHANRAJ. R. S*.AND SUJATHA. P. S.</authors>
<keywords>Ae.aegypti. S.alata, qualitative phytochemical analysis, GC-MS analysis, larvicidal, ovicidal and  ovipositional deterrence
</keywords>
<pages>244-255</pages>
</article>
</Journal>
