<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 9 Issue 1</issue_number>
<issue_period>2018 (January-March)</issue_period>
<title><b>In vitro cytotoxicity and anthocyanin studies on Pithecellobium Dulce (ROXB.) Benth (Fruits)</b> <b>against mcf 7 cell lines</b></title>
<abstract>The aim of the study was to find out the anthocyanin and anticancer efficacy of  lessThan i greaterThan Pithecellobium dulce lessThan /i greaterThan  (Roxb.) Benth fruits extract against MCF -7 (Michigdan Cancer Foundation-7).Different concentration (10, 20, 30, 40, and 50 μg/ml) of methanol extract of  lessThan i greaterThan P.dulce lessThan /i greaterThan  fruits were used to assess the  lessThan i greaterThan in vitro  lessThan /i greaterThan cytotoxic effect using 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay.  lessThan i greaterThan Pithecellobium dulce lessThan /i greaterThan  fruits contain 6.23 % of anthocyanin. The various concentrations of crude methanol extract (10, 20, 30, 40, and 50 μg/ml concentration) of  lessThan i greaterThan Pithecellobium dulce lessThan /i greaterThan  fruits were performed for cytotoxic activity. The effect of inhibition of cell growth showed significantly cytotoxic against MCF-7 cell line with an inhibit cell growth by 50% (IC50) of 24μg/ml.The present study concludes that the methanol extract of  lessThan i greaterThan Pithecellobium dulce lessThan /i greaterThan  fruits possess potent cytotoxic activity.</abstract>
<authors>A. SUGANTHI AND R. MARY JOSEPHINE</authors>
<keywords>Pithecellobium dulce, Anthocyanin, cytotoxic and MCF -7</keywords>
<pages>111-115</pages>
</article>
</Journal>
