10.22376/ijpbs.2019.10.1.p1-12 Volume 8 Issue 4 2017 (October - December) Zinc Oxide lessThan sub greaterThan lessThan /sub greaterThan nanoparticles have been proven to be competent antibacterial and antifungal activity for medical applications because of their strong redox ability, nontoxicity, long-term stability and low cost. Spherical ZnO nanoparticles were synthesized by eco-friendly green combustion method using citrate containing lessThan i greaterThan Artocarpus lessThan /i greaterThan lessThan i greaterThan gomezianus lessThan /i greaterThan fruit extract as a fuel. Prepared ZnO nanoparticles exhibit significant antibactericidal activity against lessThan i greaterThan Bacillus cereus, Escherichia coli, Serratia lessThan /i greaterThan lessThan i greaterThan marcescens lessThan /i greaterThan and antifungal activity against lessThan i greaterThan Malassezia furfur lessThan /i greaterThan using the zone of inhibition method lessThan i greaterThan . lessThan /i greaterThan The study successfully demonstrates synthesis of spherical ZnO nanoparticles by simple eco-friendly green combustion method exhibit antimicrobial activities. Further, this method can effectively need for the preparations of ZnO for the medical applications in controlling pathogenic bacteria with better dispersion and consequently, better efficiency in food and textiles industry. R. ANITHA , K.V. RAMESH Green synthesis; ZnO nanoparticles; Antibacterial activity; Antifungal activity. 90-97