International Journal of Pharma and Bio Sciences
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editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com
10.22376/ijpbs.2019.10.1.p1-12
Volume 7 Issue 4
2016 (October - December)
Phytochemical screening and mic determination of different extracts of ichnocarpus frutescens
In response to the emergence of multi-drug resistant organisms, the discovery of novel and more efficient antimicrobial agents is primordial. The current study was aimed at determining the MIC values of Petroleumether, Hexane, Chloroform and Ethylacetate extracts of lessThan i greaterThan Ichnocarpus frutescens lessThan /i greaterThan (L). W.T. Aiton lessThan i greaterThan lessThan /i greaterThan gainst lessThan i greaterThan Staphylococcus aureus lessThan /i greaterThan , lessThan i greaterThan Klebsiella pneumoniae, Proteus mirabilis, Enterobacter aerogenes, and Streptococcus pyogenes lessThan /i greaterThan . Phytochemical screening of the extracts was according to the described methods. Phytochemical screening of extracts reveals the presence of alkaloids, tannins, phenols and flavonoids. Flavonoids are absent in chloroform extract. Among all the tested extracts, ethyl acetate extract has shown the lowest MIC value. The MIC values of ethylacetate extract against lessThan i greaterThan Staphylococcus aureus, Proteus mirabilis lessThan /i greaterThan and lessThan i greaterThan Klebsiella pneumoniae lessThan /i greaterThan were found to be 256µg/mL, 128µg/mL and 512µg/mL respectively. The results of present study give baseline information for therapeutic use of lessThan i greaterThan Ichnocarpus frutescens. lessThan /i greaterThan
M.SRUJANA AND N.LAKSHMIDEVI
Antimicrobial, MIC, Phytochemicals, Ethyl acetate, Chloroform, Phenols
949-953