10.22376/ijpbs.2019.10.1.p1-12 Volume 7 Issue 2 2016 (April - June) A simple, specific and accurate reverse phase high performance liquid chromatographic method was developed for the determination Abiraterone Acetate in pharmaceutical dosage form. The column used was Hypersil ODS C18 (4.6 x 150mm, 5 mm,) in isocratic mode, with mobile phase containing phosphate buffer adjusted the pH-3.0 with orthophosphoric acid and Acetonitrile ratio of (50%:50%) the flow rate was 1.0 mL/ min and eluents was monitored at 254nm. The retention time Abiraterone was 4.858 min. The linearity for Abiraterone was in the range of 10-30 µg/ml respectively. The recovery of Abiraterone was found to be 99.5%, respectively. The proposed method was validated and successfully applied to the estimation of Abiraterone in tablet dosage form. Mass and FTIR analysis performed to determine Abiraterone Acetate in pharmaceutical dosage form. ARUN KUMAR KUNA*, S. GANAPATY AND G.V. RADHA Abiraterone Acetate, RP-HPLC, Validation 57-61