10.22376/ijpbs.2019.10.1.p1-12 Volume 1 Issue 3 2010 (July - September) Aims: The objective of this study was to utilize C - peptide levels to identify the patients suspected of having latent autoimmune diabetes in adults from clinically diagnosed type 2 diabetics. Methods:100 type 2 DM patients and 100 healthy controls were selected. All patients were assessed for fasting Cpeptide and insulin levels. Patients having C-peptide level lessThan 0.7 ng/ml were classified as suspected LADA subgroup. All patients were followed up six months later for fasting C- peptide and insulin levels along with insulin resistance. Results: 34% of the patients in the study group were classified as suspected LADA group while the rest of the patients in the study group (n = 66) were named as classic type 2 DM. There was a significant difference in the levels of C – peptide and insulin as well as insulin resistance between the suspected LADA group and classic type 2 DM patients, which was maintained on, follow up. Conclusions: C-peptide can be used as an important screening tool for autoimmunity. lessThan br / greaterThan Shakti Aggarwal, Atul Goel and Anju Jain Latent autoimmune diabetes in adults, type 2 Diabetes Mellitus, Glutamic Acid Decarboxylase antibody, C – peptide -