<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 7 Issue 1</issue_number>
<issue_period>2016 (January - March)</issue_period>
<title>SYNTHESIS OF NOVEL PYRAZOLINES BEARING TRICHLOROPHENYL MOIETY AS ANTIMICROBIAL AGENTS </title>
<abstract>In view of developing novel and effective antimicrobial agents, novel series of pyrazolines (4a-g and 5a-g) bearing 2,3,4-trichlorophenyl moiety were synthesized by treating 1-(2,3,4-trichlorophenyl)-3-(4-aryl)-2-propene-1-ones (3) with hydrazine hydrate and formic acid/ acetic acid (Schemes 1 and 2). The newly synthesized compounds were characterized by elemental analysis and spectroscopic studies and screened for their  lessThan i greaterThan in vitro lessThan /i greaterThan  antibacterial and antifungal activities. The screening studies revealed that the novel pyrazoline derivatives (4a-g and 5a-g) exhibited moderate to good activity.</abstract>
<authors>LAXMANA K, SURESH P. NAYAK, JAGADEESH PRASAD D, PRAKASH ANIL CASTELINO, KUMARA CHALUVAIAH AND SUCHETHA KUMARI</authors>
<keywords>Formylpyrazoline, Acetylpyrazoline, Antimicrobial Activity, Spectroscopic Data.</keywords>
<pages>32-39</pages>
</article>
</Journal>
