10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 4 2015 (October - December) Crude and ethyl acetate extracts of mature leaves of lessThan i greaterThan Annona reticulata lessThan /i greaterThan Linn. ( lessThan i greaterThan A. reticulata lessThan /i greaterThan ) were investigated to establish their biocontrol potentialities under laboratory condition against larvae (different instars) and pupae of lessThan i greaterThan Culex quinquefasciatus lessThan /i greaterThan Say, 1823 ( lessThan i greaterThan Cx. quinquefasciatus lessThan /i greaterThan ) at different concentrations. Crude as well as ethyl acetate extracts showed excellent larvicidal activity at remarkable low concentrations. Oviposition deterrent activity of ethyl acetate extract and smoke toxicity effect of mature leaf powdered coils on adult mosquitoes were also examined and showed an excellent result. Pupae also showed motality at low concentrations. LC lessThan sub greaterThan 50 lessThan /sub greaterThan and LC lessThan sub greaterThan 90 lessThan /sub greaterThan values of larvicidal and pupicidal activity gradually decreased with increased exposure period. Statistical justifications were done through Log-probit, regression and ANOVA analyses. No adverse effect has been found on tested non target organisms. Photochemical analyses of leaf extracts revealed the presence of different secondary metabolites. So, crude and ethyl acetate leaf extracts of lessThan i greaterThan A. reticulata lessThan /i greaterThan can effectively be used as larvicide, pupicide, oviposition deterrent activity and smoke toxicity against lessThan i greaterThan Cx. quinquefasciatus lessThan /i greaterThan mosquito species. SUBRATA MALLICK AND GOUTAM CHANDRA Annona reticulata, Culex quinquefasciatus, larvicidal, pupicidal, oviposition deterrent activity, smoke toxicity, phytochemicals 244-253