10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 3 2015 (July - September) In the present study, the chemical composition and lessThan i greaterThan in vitro lessThan /i greaterThan antioxidant activity of methanol extract of seeds of lessThan i greaterThan Entada phaseoloides lessThan /i greaterThan were analyzed by various lessThan i greaterThan in vitro lessThan /i greaterThan antioxidant models lessThan i greaterThan viz. lessThan /i greaterThan DPPH radical FRAP and ABTS assay along with the evaluation of IC lessThan sub greaterThan 50 lessThan /sub greaterThan value. Screening of the phytochemical constituents and high performance liquid chromatography (HPLC) analysis of the methanol extract of lessThan i greaterThan Entada phaseoloides lessThan /i greaterThan were performed for identification of some of the functional compounds present in the seeds. The methanol extract of lessThan i greaterThan Entada phaseoloides lessThan /i greaterThan exhibited a significant ascending trend of percentage inhibition with maximum activity at 60μg/ml and 80μg/ml concentration for all the models of free radical scavenging activity. The results showed high amount of phenolic and flavonoids, confirmed by HPLC analysis, and thus it might be an alternative to the synthetic antioxidants available in the market. The chemical composition analysis revealed a high quantity of protein, carbohydrate, fat and minerals. The results demonstrated that the seeds of lessThan i greaterThan Entada phaseoloides lessThan /i greaterThan exhibits an excellent antioxidant activity with high level of nutrients and thus presents a great potential as a source of highly nutritious potent natural antioxidants. CHANDANA CHOUDHURY BARUA, MOUSUMI HAZORIKA, JYOTI MISRI, SUPARNA SEN, MONDIRA BORA, BIBEKA NANDA SAIKIA AND MINESWAR HAZARIKA Antioxidant activity, chemical composition, phytochemical constituents, Entada phaseoloides, HPLC 366-376