10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 3 2015 (July - September) Myristica fragrans (Nutmeg) had been reported to have various effects on different organs. This work was therefore conducted to evaluate the antidiarrheal and sedative effects of Myristica fragrans (Nutmeg) an herbal medicine in albino rats. The antidiarrheal effect of Myristica fragrans evaluated by the comparison of total count of feces discharged during 5 hours after castor oil administration in different groups of albino rats. The sedative effect of Myristica fragrans evaluated by the observation of righting reflex and the duration of hypnosis after administration of pentobarbitone in different groups of albino rats. The results of our study indicate that Nutmeg have antidiarrhoeal and some sedative effects. DR. RAJENDRA GUPTA Nutmeg, Myristica fragrans, Diarrhoea. 148-151