10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 3 2015 (July - September) Sarcoma itself is a rare entity in intraoral region and osteosarcoma is not an exception from this data. Here we are presenting a case of osteosarcoma in a 31 year old newly married young male which was simply presented as toothache and so that primarily misdiagnosed as dental infection. With a battery of investigations like Orthopentogram, FNA, Histopathological Examination, CT scan etc, ultimately we reached our diagnosis & an oncological plan was made to treat him with multiple neo-adjuvant chemotherapy followed by radical surgical resection along with a margin of normal surrounding tissue, and chemotherapy. DR. KOUSHIK DEWAN AND DR. TANUSHREE MONDAL Osteosarcoma, Orthopentogram, Fine needle aspiration cytology (FNA). 612-617