<?xml version="1.0" encoding="utf-8"?>
<Journal>
<Journal-Info>
<name>International Journal of Pharma and Bio Sciences</name>
<website>ijpbs.net</website>
<email>editorijpbs@rediffmail.com (or) editorofijpbs@yahoo.com (or) prasmol@rediffmail.com</email>
</Journal-Info>
<article>
<article-id pub-id-type='other'>10.22376/ijpbs.2019.10.1.p1-12</article-id>
<issue_number>Volume 6 Issue 3</issue_number>
<issue_period>2015 (July - September)</issue_period>
<title>DETECTION OF BLANDM-1 GENE IN PROVIDENCIA RETTGERI ISOLATED FROM DIABETIC FOOT ULCERS OF FOUR PATIENTS FROM INDIA </title>
<abstract> lessThan i greaterThan Providencia rettgeri lessThan /i greaterThan  is associated with various infections, including skin infections, diarrhea, bacteremia and urinary tract infections (UTI) andmany hospital acquired infections. Carbapenems are mainstay of treatment fordrug resistant bacterial infections. Enzyme New Delhi Metallo β Lactamase-1encoded by the gene  lessThan i greaterThan bla lessThan /i greaterThan  lessThan sub greaterThan NDM-1 lessThan /sub greaterThan  make these bacteria resistant to carbapenems. This gene is located ontransmissible plasmid which may include other antibiotic resistance genes.A total of four strains of  lessThan i greaterThan Providencia rettgeri lessThan /i greaterThan was isolated from the wound swabs ofpatients with diabetic foot ulcer. They were screened for the production of carbapenemase and confirmed byPolymerase Chain Reaction amplification and sequencing the  lessThan i greaterThan bla lessThan /i greaterThan  lessThan sub greaterThan NDM-1 lessThan /sub greaterThan  gene. Presence of this gene can be a potential risk factor in management of diabetic foot infections, which can lead to systemic toxicity and setting of gangrene. To our knowledge this is the first report of lessThan i greaterThan Providencia rettgeri lessThan /i greaterThan  with  lessThan i greaterThan bla lessThan /i greaterThan  lessThan sub greaterThan NDM-1 lessThan /sub greaterThan  isolated from diabetic patients in India.</abstract>
<authors>SAMANT SA, MARATHE N AND VAISHAMPAYAN A</authors>
<keywords>Providencia rettgeri, Diabetic foot ulcer, NDM Î² Lactamase, blaNDM-1</keywords>
<pages>125-130</pages>
</article>
</Journal>
