International Journal of Pharma and Bio Sciences
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10.22376/ijpbs.2019.10.1.p1-12
Volume 6 Issue 2
2015 (April - June)
A STUDY OF LIPID PROFILE IN PATIENTS SUFFERING FROM PSORIASISAS A MARKER OF CARDIOVASCULAR DISEASE RISK
Diabetes and obesity are associated with endothelial dysfunction and dyslipidaemia due to chronic inflammation. Both of them impart the risk to develop atherosclerotic cardiovascular disease. Psoriasis is a chronic inflammatory disease involving skin. The aim of this study is to find out the occurrence of dyslipidaemia in psoriatic individuals and there by risk assessment of developing cardiovascular disease amongst them. Objective:To measure fasting lipid profile in patients suffering from psoriasis. 50 diagnosedpatients of psoriasis were designated as cases and 50 normal, healthy individuals as controls. Anthropometric measurement (Body Mass Index) and biochemical estimations (fasting blood glucose and lipid profile) were carried out. Statistically significant difference was observed in levels of fasting blood glucose, total cholesterol, LDL, total cholesterol/HDL and LDL/HDL ratio in cases compared to controls. Psoriatic individuals tend to develop dyslipidaemia which can influence the process of atherosclerosis and impart cardiovascular risk.
DR. HASIT LAD, DR. JIGNESH GORASIYA, MISS BHAVISHA RANA, DR. VILAS U. CHAVAN, DR. DILIP KAVA AND DR. DVSS RAMAVATARAM
Psoriasis, Chronic inflammation, Dyslipidaemia, Atherosclerosis, Cardiovascular disease.
1226-1232