10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 2 2015 (April - June) The objective of this paper is to review the modalities of management employed following an accidental exposure to the fatal blood-borne pathogen -Hepatitis B virus. An online search of literature was carried out using the keywords: "Hepatitis B"," Occupational Exposure", "Post -exposure prophylaxis". The information about the post -exposure management against hepatitis B virus in dental office was reviewed. DR.M.P.SANTHOSH KUMAR M.D.S. Hepatitis B virus, Exposure, Management 938-944