10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 2 2015 (April - June) The marine diatom C lessThan i greaterThan ymbella lessThan /i greaterThan sp. isolated from the coastal water of Mahabalipuram Beach, Chennai, and Tamilnadu was made as unialgal and investigated for growth. The culture is grown aseptically in F/2 medium under constant temperature and light. Before carrying out the studies, the fatty acid, carbohydrates, cellular dry mass and pigments of the mother culture were analyzed. The scope of this study was "The effect of Aculeacin A in fatty acid synthesis of marine diatom C lessThan i greaterThan ymbella lessThan /i greaterThan sp." Different concentrations of Aculeacin A with respect to time towards cellular growth, dry mass and fatty acids were studied. The experimental evidence shows, the control of metabolic pathways during the various phases of Aculeacin A treatment. This review focuses on the contribution of inhibitor or compound, in our understanding of the mechanism by which Aculeacin A induces the metabolic pathway of marine diatom C lessThan i greaterThan ymbella lessThan /i greaterThan sp. JAGANNATHAN NARAYANASWAMY Algae, Cymbella, Aculeacin A, Fatty acids, Diatom. 513-521