10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 2 2015 (April - June) The potent antibacterial and antiviral activity of petroleum ether, ethyl acetate, successive and crude methanolic extracts of lessThan i greaterThan J. curcas lessThan /i greaterThan leaves was evaluated. The antibacterial activity of lessThan i greaterThan J. curcas lessThan /i greaterThan extracts was studied against 6 common foods borne bacteria using disc diffusion assay. The antibacterial activity of lessThan i greaterThan J. curcas lessThan /i greaterThan extracts showed different degrees of inhibition zone against the pathogens bacteria. Yet, successive methanolic and ethyl acetate extracts were effective against most of the tested strains. Additionally, all lessThan i greaterThan J. curcas lessThan /i greaterThan extracts were evaluated against the highly pathogenic H5N1 influenza virus (A/chicken/Egypt/M7217B/2013 (H5N1)) using plaque reduction assay. Crude methanolic extract showed antiviral activity with virucidal effect of 75% at concentration 25 µg/µl. The GC-MS analysis of petroleum ether and ethyl acetate extracts revealed the presence of major active constituents. The present study may suggest the possibility for developing new antibacterial and antiviral compounds from lessThan i greaterThan J. curcas lessThan /i greaterThan leaves. F.K. EL-BAZ , O. BAGATO, H.F. ALY, S A. SAAD,M.A. ALI AND A.A. MOHAMED Antiviral; H5N1; food borne pathogens; GC-MS; J. curcas; phytoconstituents. 108-120