10.22376/ijpbs.2019.10.1.p1-12 Volume 6 Issue 2 2015 (April - June) Dengue, also known as "Breakbone fever", is an infectious tropical disease caused by Flavi virus and is transmitted by Aedesmosquito.Approximately 2.5 billion people lessThan sup greaterThan 1 lessThan /sup greaterThan live in dengue-risk regions with about 100 million new cases each year worldwide. The cumulative dengue diseases burden has attained an unprecedented proportion in recent times with sharp increase in the size of human population at risk. About half of the world's population is at risk now.In our tertiary care center Rajiv Gandhi Government General Hospital, Chennai, we conducted a prospective study from October 2013 to December 2013, during which 75 patients with Dengue IgMpositivitity were taken into consideration. We monitored the total count, platelet count, hemoglobin, ultrasonographic imaging and hematocrit serially and the outcome of the patients were followed up till the discharge of the patients. DHANDAPANI E AND SUDHA M Thrombocytopenia, Flavivirus, Dengue shock syndrome, Dengue Hemorrhagic Fever 84-92