10.22376/ijpbs.2019.10.1.p1-12 Volume 5 Issue 4 2014 (October - December) To estimate the sero prevalence of rubella among children attending a tertiary care hospital, in the age group of 1 to 14 years who have not received MMR vaccine.This was a hospital based prospective descriptive study. Blood samples were collected from 50 children aged 1-14 years and analyzed for IgG antibody titres for rubella infection by a quantitative enzyme-linked immunosorbent assay. Data on the socio epidemiological factors was obtained from the parents. The overall rubella sero positivity rate was 58%. The sero positivity increased with age; which was 33% among 1 to 5 years, 55% among 6 to 10 years and 89% among 10 to 14 years. (P=0.01). The study provides information on the increasing sero prevalence of rubella with increasing age among unimmunized children. Since there is an overall sero positivity of only 58% among children, rubella containing vaccine should be included in the National Immunization Schedule to reduce the rubella burden. SHANTHI RAMESH, KURALARASI PRIYADARSHINI, JAGDEEP RAMESHAND D. VIJAYASEKARAN Rubella, Seroprevalence children, Vaccine, National Immunization Schedule. 1146-1149